Flipping lipids why an whats the reason for

Progress in Lipid Research , 64 , On the molecular mechanism of flippase- and scramblase-mediated phospholipid transport. Structural basis for phospholipid scrambling in the TMEM16 family. Current Opinion in Structural Biology , 39 , Lipid topogenesis — 35 years on. Mallela , Roger Schneiter , Andreas Conzelmann ,.

PLOS Genetics , 12 7 , e Model studies of lipid flip-flop in membranes. Biophysical Journal , 12 , Quek , Long N. Nguyen , Hao Fan , David L. Journal of Biological Chemistry , 18 , Regulation of Megakaryocyte and Platelet Survival.

Yang , L. Maxfield , Anant K. Intramembrane and Intermembrane Lipid Transport. Flipping a Lipid-Linked Oligosaccharide? You Must Whip It!. Trends in Biochemical Sciences , 40 12 , Application of self-consistent field theory to self-assembled bilayer membranes.

Chinese Physics B , 24 12 , Feuilloley , Nicole Orange , Hermann J. Glycerophospholipid synthesis and functions in Pseudomonas. Chemistry and Physics of Lipids , , Lipid gymnastics. Nature , , The active site of yeast phosphatidylinositol synthase Pis1 is facing the cytosol.

Biology and Assembly of the Bacterial Envelope. Ernst , Anant K. Phospholipid scrambling by rhodopsin. Lipid Flippases for Bacterial Peptidoglycan Biosynthesis. Lipid Insights , 8s1 , LPI. S Jeffrey S. S Janine D. Brunner , Novandy K. X-ray structure of a calcium-activated TMEM16 lipid scramblase.

Joseph , Jeremy S. Dittman , Vadim Cherezov , Raymond C. Stevens , Oliver P. Constitutive phospholipid scramblase activity of a G protein-coupled receptor. Journal of Bacteriology , 23 , Glycoengineering in plants for the development of N-glycan structures compatible with biopharmaceuticals. Plant Biotechnology Reports , 8 5 , A flipping cell wall ferry.

Science , , Kingston , Heng Zhao , Gregory M. Cook , John D. Accumulation of heptaprenyl diphosphate sensitizes B acillus subtilis to bacitracin: implications for the mechanism of resistance mediated by the BceAB transporter.

Molecular Microbiology , 93 1 , Holthuis , Anant K. Lipid landscapes and pipelines in membrane homeostasis. The portal can access those files and use them to remember the user's data, such as their chosen settings screen view, interface language, etc. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service.

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You can change the cookie settings in your browser. Submitting the report failed. Please, try again. Dynamic Transbilayer Lipid Asymmetry. Enzymatic trans-bilayer lipid transport: Mechanisms, efficiencies, slippage, and membrane curvature. The biosynthesis of many polysaccharides, including bacterial peptidoglycan and eukaryotic N-linked glycans, requires transport of lipid-linked oligosaccharide LLO precursors across the membrane by … Expand.

Specific proteins are required to translocate phosphatidylcholine bidirectionally across the endoplasmic reticulum. View 2 excerpts, references background. Lipid flippases and their biological functions. New fluorescent probes reveal that flippase-mediated flip-flop of phosphatidylinositol across the endoplasmic reticulum membrane does not depend on the stereochemistry of the lipid. View 1 excerpt, references background.

View 13 excerpts, references background. How lipid flippases can modulate membrane structure. Most predicted biogenic membrane flippases have not been identified at the molecular level, and the few flippases that have been identified by genetic approaches have not been biochemically validated. Here we summarize recent progress on this fundamental topic and speculate on the mechanism s by which biogenic membrane flippases facilitate transbilayer lipid movement.